Trends in Immunotherapy

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Review on phytochemical constituents of the genus Trichilia and biological activities

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https://doi.org/10.24294/ti.v8.i1.2434
Tuz Zohora, F., Sultana Joya, I., Ahmed Bhuiyan, M., Mahmood Hasan, C., & Ahsan, M. (2024). Review on phytochemical constituents of the genus Trichilia and biological activities. Trends in Immunotherapy, 8(1). https://doi.org/10.24294/ti.v8.i1.2434
Volume 8 Issue 1 (2024)
Copyright (c) 2024 Fatema Tuz Zohora, Irin Sultana Joya, Mohiuddin Ahmed Bhuiyan, Choudhury Mahmood Hasan, Monira Ahsan
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Authors

  • Fatema Tuz Zohora
    Department of Pharmacy, University of Asia Pacific, Dhaka 1205, Bangladesh
  • Irin Sultana Joya Department of Pharmacy, Primeasia University, Dhaka 1213, Bangladesh
  • Mohiuddin Ahmed Bhuiyan Department of Pharmacy, University of Asia Pacific, Dhaka 1205, Bangladesh
  • Choudhury Mahmood Hasan Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • Monira Ahsan Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

Studies conducted on the chemical composition of the genus Trichilia have isolated and identified 334 different compounds such as monoterpenes, diterpenes, sesquiterpenes, triterpenes, limonoids, steroids, coumarins, lignans, flavonoids, amino acid, phenolic acids, and lactones. This genus is used in traditional medicine for the manufacture of antibacterial, antioxidant, antiviral and antimalarial drugs. Indeed, our research with numerous Trichilia species has revealed that these plants exhibit antioxidant, antibacterial, anticholinesterase, neuroprotective, anti-inflammatory, and anti-anaphylactic properties against pathogens of major clinical value. The properties of analgesia, liver protection, and immunomodulation are also being studied. This study summarizes the main therapeutic uses of Genus Trichilia of species mentioned in the article and encourages future research into their usage in the treatment of various ailments as antimicrobial and anticancer.

Keywords:

Trichilia secondary metabolites biological activities antimicrobial anticancer

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