Trends in Immunotherapy

Case Report

A case of unilateral epidermal nevi complicated by atopic dermatitis treated with dupilumab

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https://doi.org/10.24294/ti.v8.i1.2773
Nagatsuka, Y., Nakashima, C., Kitayama, N., Ishida, Y., Kabashima, K., & Otsuka, A. (2023). A case of unilateral epidermal nevi complicated by atopic dermatitis treated with dupilumab. Trends in Immunotherapy, 8(1). https://doi.org/10.24294/ti.v8.i1.2773
Volume 8 Issue 1 (2024)
Copyright (c) 2023 Yumi Nagatsuka, Chisa Nakashima, Naomi Kitayama, Yoshio Ishida, Kenji Kabashima, Atsushi Otsuka
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Authors

  • Yumi Nagatsuka Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka 589-8511, Japan
  • Chisa Nakashima
    Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka 589-8511, Japan
  • Naomi Kitayama Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka 589-8511, Japan; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
  • Yoshio Ishida Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
  • Kenji Kabashima Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan
  • Atsushi Otsuka Department of Dermatology, Faculty of Medicine, Kindai University Hospital, Osaka 589-8511, Japan

Epidermal Nevus Syndrome (ENS) is a congenital disorder characterized by skin lesions called epidermal nevi. This condition typically appears at birth or in infancy. However, a case of adult‐onset epidermal nevi was reported in a 36‐year‐old male with a history of atopic dermatitis (AD) and skin abnormalities on the right side of his body. He had been using topical steroids for AD but eventually started dupilumab treatment at age 41. The treatment led to significant improvements in his skin condition, including a reduction in erythema and scaling. Laboratory tests also showed improvement in serum Immunoglobulin E (IgE) levels and other markers. We report with a literature review.

Keywords:

atopic dermatitis epidermal nevi dupilumab unilateral

References

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