Trends in Immunotherapy

Case Report

A pediatric case of exudative erythema multiforme probably associated with asymptomatic COVID-19

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https://doi.org/10.24294/ti.v7.i2.2397
Wada, Y., Minami, K., Natsuaki, M., & Kanazawa, N. (2023). A pediatric case of exudative erythema multiforme probably associated with asymptomatic COVID-19. Trends in Immunotherapy, 7(2). https://doi.org/10.24294/ti.v7.i2.2397
Volume 7 Issue 2 (2023)

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Authors

  • Yoshihiro Wada Department of Dermatology, Hyogo Medical University, Nishinomiya 663-8501, Japan
  • Kayoko Minami Department of Dermatology, Uegahara Hospital, Nishinomiya 662-0884, Japan
  • Masaru Natsuaki Department of Dermatology, Hyogo Medical University, Nishinomiya 663-8501, Japan
  • Nobuo Kanazawa
    Department of Dermatology, Hyogo Medical University, Nishinomiya 663-8501, Japan

COVID-19 is a pandemic involving severe acute respiratory syndrome-coronavirus SARS-CoV-2, which started in China at the end of 2019 and has spread globally. Among COVID-19 patients, 17.8% are under 20 years of age. Most children infected with SARS-CoV-2 are asymptomatic or only oligosymptomatic and can easily be overlooked. We followed an 11-year-old boy showing exudative erythema multiforme, which appeared during isolation at home following a positive polymerase chain reaction (PCR) test for COVID-19. Our case, although otherwise asymptomatic, showed typical clinical and histological manifestations of the erythema multiforme-like lesions associated with COVID-19. The presence of such an asymptomatic SARS-CoV-2 carrier who developed erythema multiforme-like skin lesions provides the possibility that some undefined infectious organisms, such as SARS-CoV-2, could be the origin of exudative erythema multiforme cases without any apparent cause.

Keywords:

COVID-19 severe acute respiratory syndrome-coronavirus-2 polymerase chain reaction asymptomatic exudative erythema multiforme

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