With the maturity and popularity of network technology and multimedia technology, more and more communication tools and means have entered people’s lives. The usual communication tools are often limited to the ability to transmit sound signals. This method does not well express the information between the two parties in some special occasions, such as a noisy environment, where both parties have language or hearing impairments. The multimedia communication system is a technology that combines network communication and multimedia. It utilizes the efficiency of data transmission over the network and the diversity of information in multimedia, making communication between people faster, clearer, and more intuitive. The multimedia communication system is an important part of the application to the intelligent transportation system. Intelligent transportation system is a systematic, real-time, accurate, interactive, and extensive traffic management system established by the comprehensive use of modern high and new technology in the transportation system. With these characteristics, intelligent transportation system has increasingly become an important means to solve modern traffic problems. Based on multimedia communication and intelligent transportation system, this article optimizes the vehicle path and realizes the application of intelligent transportation.