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Clinical Research

A great mimicker of mastoiditis: Multisystem Langerhans’ cell histiocytosis

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Seong Kin, F., Cheng Ai, O., Arbaeyah Hussain, F., & Bee See, G. (2020). A great mimicker of mastoiditis: Multisystem Langerhans’ cell histiocytosis. ENT Updates, 10(1). https://doi.org/10.32448/entupdates.673014

Authors

  • Foong Seong Kin Department of ORL-HNS, Queen Elizabeth Hospital, Sabah, Malaysia
  • Ong Cheng Ai Department of ORL-HNS, Queen Elizabeth Hospital, Sabah, Malaysia
  • Faezahtul Arbaeyah Hussain Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, Kelantan, Malaysia
  • Goh Bee See
    Department of ORL-HNS, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia

Langerhans’ cell histiocytosis (LCH) is a rare group of diseases characterized by abnormal clonal proliferation of Langerhans cells in one or more systems. LCH can occur in any system. We report a case of bilateral otologic LCH that presented as a case of mastoiditis. Despite multiple courses of antibiotics, there was no improvement. Subsequent excision biopsy of a postauricular mass confirmed the diagnosis of LCH. The patient responded well to chemotherapy

Keywords:

Histiocytosis Langerhans-Cell otological diseases mastoiditis.