ENT Updates

Clinical Research

Evaluation of the correlation of 25-hydroxyvitamin-D serum levels with allergic rhinitis

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https://doi.org/10.2399/jmu.2015001005
Yalçınkaya, E., Emin Tunçkaşık, M., Güler, İsmail, Kocatürk, S., & Gündüz, Özge. (2015). Evaluation of the correlation of 25-hydroxyvitamin-D serum levels with allergic rhinitis. ENT Updates, 5(1). https://doi.org/10.2399/jmu.2015001005
Volume 5 Issue 1 (2015)
Copyright (c) 2015 Esin Yalçınkaya, Mehmet Emin Tunçkaşık, İsmail Güler, Sinan Kocatürk, Özge Gündüz
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors

  • Esin Yalçınkaya
    Department of Otorhinolaryngology, Faculty of Medicine, Ufuk University, Ankara, Turkey
  • Mehmet Emin Tunçkaşık Department of Otorhinolaryngology, Faculty of Medicine, Ufuk University, Ankara, Turkey
  • İsmail Güler Department of Otorhinolaryngology, Faculty of Medicine, Ufuk University, Ankara, Turkey
  • Sinan Kocatürk Department of Otorhinolaryngology, Faculty of Medicine, Ufuk University, Ankara, Turkey
  • Özge Gündüz Department of Dermatology, Faculty of Medicine, Ufuk University, Ankara, Turkey

Objective: Recent studies point to a relationship between allergic diseases and vitamin D deficiency. This relationship seems to be associated with immune-modulator effects of the derivatives of vitamin D. However, there are limited number of studies on the relationship between allergic rhinitis and derivatives of vitamin D. We planned our study to investigate this issue.

Methods: The study group was composed of 30 patients diagnosed with allergic rhinitis according to ARIA (Allergic Rhinitis and its Impact on Asthma) Criteria. The control group included 30 patients of the same age and gender without any allergic rhinitis disease. The patients with an underlying disease which may cause deficiency of calcium and vitamin D were excluded. The significance of the difference between study and control groups in terms of serum 25-hydroxy (OH) vitamin D levels was also evaluated.

Results: It was determined that the levels of vitamin D were within normal (10–90 ng/mL) limits in both groups. It was found out that the mean serum 25(OH)vitamin D level (15.39 ng/mL) of the study group was significantly lower than the control group (53.80 ng/mL) (p=0.00). No significant difference was found between the genders in terms of vitamin D levels (p=0.398).

Conclusion: It is necessary to do more researches on the effects of vitamin D derivatives on allergic rhinitis. This study indicates that a vitamin D deficiency should be taken into consideration during the treatment for resistant allergic rhinitis patients.

Keywords:

Allergic rhinitis 25-hydroxyvitamin D allergic diseases