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Clinical Research

Does the site of aspiration affect the efficacy of ultrasound-guided fine needle aspiration biopsy of thyroid nodules?

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https://doi.org/10.2399/jmu.2015001004
Çakmakcı, E., Tokgöz Özal, S., Kolçak Türkoğlu, Özlem, Uçan, B., Kaygusuz, U., Dinç, T., & Ece, D. (2015). Does the site of aspiration affect the efficacy of ultrasound-guided fine needle aspiration biopsy of thyroid nodules?. ENT Updates, 5(1). https://doi.org/10.2399/jmu.2015001004
Volume 5 Issue 1 (2015)
Copyright (c) 2015 Emin Çakmakcı, Safiye Tokgöz Özal, Özlem Kolçak Türkoğlu, Berna Uçan, Umut Kaygusuz, Tolga Dinç, Dilek Ece
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors

  • Emin Çakmakcı
    Department of Radiology, Kelkit Government Hospital, Gümüşhane, Turkey
  • Safiye Tokgöz Özal Department of Radiology, Istanbul Dr. Lütfi Kırdar Kartal Training and Research Hospital, Istanbul, Turkey
  • Özlem Kolçak Türkoğlu Department of Radiology, Istanbul Dr. Lütfi Kırdar Kartal Training and Research Hospital, Istanbul, Turkey
  • Berna Uçan Department of Radiology, Dr. Sami Ulus Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
  • Umut Kaygusuz Department of Otorhinolaryngology, Dr. Sami Ulus Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
  • Tolga Dinç Department of General Surgery, Dr. Sami Ulus Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
  • Dilek Ece Department of Pathology, Istanbul Dr. Lütfi K›rdar Kartal Training and Research Hospital, Istanbul, Turkey

Objective: To investigate whether the choice of a hypovascular or a hypervascular site of a thyroid nodule affects the efficacy of the ultrasound-guided fine needle aspiration procedure or not.

Methods: Sixty solid thyroid nodules in 60 patients with hypo- and hypervascular parts were included in this prospective clinical study. Under color Doppler sonographic guidance, the fine needle aspiration was made with 22-gauge needle. Radiological and cytological features as well as the adequacy of samples were noted and compared.

Results: Sonographically, 25 nodules (41.7%) were hetereogenous and calcified, 21 were hypoechoic (35%), 10 were isoechoic (16.7%) and 4 were hyperechoic (6.6%). Rate of adequate sampling when only hypervascular was used or hypovascular sites were evaluated were 81.7% and 83.3%, respectively. When both sites were evaluated together, rate of adequate sampling was found to be 91.7% in total. Presence and distribution of endothelial cells in the sample seems not to influence the diagnostic value of the procedure.

Conclusion: Our results indicate that vascularity of a thyroid nodule outlined by color Doppler sonography can aid in optimizing the efficiency of fine-needle aspiration biopsy. The samples obtained from aspirates of hypo- and hypervascular sites are both complementary and assessment of these sites together yields better results in terms of diagnostic accuracy.

Keywords:

Thyroid nodule diagnosis ultrasonography fine-needle aspiration color Doppler