ENT Updates

Clinical Research

Results of 24-hour pH monitorization in laryngopharyngeal reflux cases presenting with various symptoms

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https://doi.org/10.2399/jmu.2012003004
Kar, M., San, İmran, Korkmaz, B., Özgönül, A., & İynen, İsmail. (2012). Results of 24-hour pH monitorization in laryngopharyngeal reflux cases presenting with various symptoms. ENT Updates, 2(3). https://doi.org/10.2399/jmu.2012003004
Volume 2 Issue 3 (2012)
Copyright (c) 2012 Murat Kar, İmran San, Baki Korkmaz, Abdullah Özgönül, İsmail İynen
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors

  • Murat Kar
    Harran Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Şanlıurfa
  • İmran San Harran Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Şanlıurfa
  • Baki Korkmaz Harran Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Şanlıurfa
  • Abdullah Özgönül Harran Üniversitesi Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Şanlıurfa
  • İsmail İynen Harran Üniversitesi Tıp Fakültesi, Kulak Burun Boğaz Hastalıkları Anabilim Dalı, Şanlıurfa

Objective: Laryngopharyngeal reflux (LPR), an atypical form of gastroesophageal reflux (GER), may present with non-specific symptoms of upper aerodigestive system. In this study, we aimed to show the LPR frequency of various symptom groups by 24-hour double-channel pH monitorization.

Methods: A total of 125 patients and 20 healthy controls were enrolled to this study between July 2007 and July 2008. Patients were assigned to 5 different groups with respect to their chief complaints (gastrointestinal, bronchial, laryngeal, pharyngeal and rhinologic). All patients underwent 24-hour double-channel pH monitorization and diagnosis of LPR was confirmed if one or more pH results were below 4.0 in proximal channel.

Results: Laryngopharyngeal reflux was detected in 18 of 19 patients (94%) in gastrointestinal group, 24 of 25 patients (96%) in bronchial group, 26 of 31 patients (83%) in laryngeal group, 27 of 29 patients (93%) in pharyngeal group, 19 of 21 patients (90%) in rhinologic group and 2 of 20 patients (10%) in the control group. The highest incidence of LPR was encountered in the bronchial group, whereas the lowest incidence for LPR was detected in laryngeal group.

Conclusion: Laryngopharyngeal reflux may present with a wide spectrum of symptoms in daily otorhinolaryngology practice. With respect to our results, 24-hour double-channel pH monitorization turns out to be a reliable method in the diagnosis of LPR in cases suspected for laryngopharyngeal reflux.

Keywords:

Laryngopharyngeal reflux gastroesophageal reflux diagnosis 24-hour pH monitorization