Chronic rhinosinusitis with nasal polyps (CRSwNP) and allergic rhinitis (AR) are common upper-airway inflammatory disorders that often coexist, significantly decrease quality of life, and recur even when treated with intranasal or systemic therapy or surgery. Growing mechanistic insights, such as the role of type 2 inflammation driven by epithelial “alarmins” (TSLP, IL-25, IL-33) and downstream...

Nicotine is a stimulant that affects the ganglia. Similar to capsaicin, it also activates sensory nerves in the airways, which leads to secretion and coughing in human subjects. The nasal mucosa can be exposed to the drug through either nasal or oral administration. The study investigated the effects of nicotine on electrically stimulated contractions of human nasal mucosa, resting tension of h...

The diagnosis of vocal fold (VF) lesions relies on examinations such as laryngoscopy and voice analysis, which are highly dependent on clinicians' experience. This leads to a relatively higher risk of misdiagnosis and missed diagnosis among junior physicians. In recent years, with the rapid advancement of artificial intelligence (AI), numerous deep learning (DL)-based methods have emerged in th...