Objective: To present new information to the literature by imaging the calcospherule forming tympanosclerotic plaque's structure with atomic force microscope and to analyze the elementary structure of it with energy dispersive X-ray detector adapted to the scanning electron microscope.

Methods: Samples taken from 30 patients who underwent surgery for ty...

Objective: To develop an experimental acute suppurative otitis media model and compare the responses of rats to penicillin and combinations of leukotriene antagonist with respect to histopathological observations conducted at both early and late phases.

Methods: A total of eighty-three ears from fifty six Wistar rats used in this study. Pneumococcus sus...

Objective: Effective premedication is one of the key factors for anesthetic management of autistic children. We designed a study protocol to compare two different dose regimens of midazolam plus ketamine for premedication of autistic children.

Methods: We performed a prospective randomized double-blind study in 142 autistic children, aged 1-17 years, un...

Objective: Laryngopharyngeal reflux (LPR), an atypical form of gastroesophageal reflux (GER), may present with non-specific symptoms of upper aerodigestive system. In this study, we aimed to show the LPR frequency of various symptom groups by 24-hour double-channel pH monitorization.

Methods: A total of 125 patients and 20 healthy controls were enrolled...

Objective: We aimed to compare the efficacy of temporalis muscle fascia and tragal cartilage island grafts after tympanoplasty in terms of functional hearing outcomes and tympanometric findings.

Methods: A total of 42 patients were enrolled in this study and Group 1 including 14 patients was defined as fascia group while Group 2 including 28 patients wa...

Angiofibromas typically arise from the nasopharynx in young adolescent males. Extranasopharyngeal angiofibroma (ENA) implicates the vascular fibrous nodules occurring outside the nasopharynx. Since the clinical characteristics of ENA differ from those of nasopharyngeal angiofibroma, diagnosis can be challenging. Biopsy is usually discouraged due to the risk of bleeding. A high index of suspicio...

The conventional treatment modalities are surgery and/or radiation therapy in patients with early stage squamous cell carcinoma of the supraglottic larynx. In the literature, there are different opinions about the success of chemotherapy regimens with curative or inductive intent in patients with early stage laryngeal carcinoma. In this case report, a patient with T2N0M0 squamous cell carcinoma...