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Evaluation of olfactory function in migraineurs during the migraine-free period with odor identification test

Hakan Tekeli
Department of Neurology, GATA Haydarpaşa Training Hospital, Istanbul, Turkey
Mehmet Güney Şenol
Department of Neurology, GATA Haydarpaşa Training Hospital, Istanbul, Turkey
Fatih Özdağ
Department of Neurology, GATA Haydarpaşa Training Hospital, Istanbul, Turkey
Mehmet Saraçoğlu
Division of Neurology, Istanbul Surgery Hospital, Istanbul, Turkey
Halit Yaşar
Division of Neurology, GATA Mevki Hospital, Ankara, Turkey
Mustafa Tansel Kendirli
Department of Neurology, GATA Haydarpaşa Training Hospital, Istanbul, Turkey
Aytuğ Altundağ
Division of Otorhinolaryngology, Istanbul Surgery Hospital, Istanbul, Turkey
Melih Çayönü
Department of Otorhinolaryngology, Amasya University Training and Research Hospital, Amasya, Turkey
Murat Salihoğlu
Department of Otorhinolaryngology, GATA Haydarpaşa Training Hospital, Istanbul, Turkey
Türker Türker
Department of Public Health, GATA Ankara Training Hospital, Ankara, Turkey
Received: 12 September 2024
Published: 02 February 2014

Abstract

Objective: Despite the fact that there are many studies about the osmophobia and migraine, we have very little knowledge about the olfactory abilities of migraineurs during the period between the attacks. So, the aim of this study was to evaluate the olfactory function of migraineurs during the period without headaches with odor identification test.

Methods: Two hundred and ninety healthy people aged 16 to 65 years (152 female, 138 male) and 84 migraine patients aged 18 to 55 years (47 female, 37 male) were studied. The participants with migraine were selected from the patients who applied to headache outpatient clinic for assessment. Participants, appropriate to the study, were physically and neurologically examined in detail and then they were taken to the test room in order to be screened with Short Smell Test Battery of GATA Haydarpaşa (GULTEST).

Results: The mean GULTEST score of the migraine group was less than the healthy group and the difference was significant. The effect of gender, cigarette smoking and disease status (migraine) on GULTEST scores was evaluated by linear regression model. It was found that females had higher odor identification scores than males in both migraineurs and controls. On the other hand, cigarette smoking had a significant negative effect on GULTEST scores. Furthermore, migraine had a significant negative effect on GULTEST scores.

Conclusion: Our study showed that even during the headache-free period, migraineurs might have reduced olfactory abilities.

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